Total synthesis of fumitremorgins and verruculogens.
HINO, T. and NAKAGAWA, M.
Heterocycles 46 : 673-704.
1997
บทคัดย่อ
A review with 81 references. The syntheses of fumitremorgin B, C, verruculogen TR-2 and related compounds, all of which are pentacyclic tremorgenic mycotoxins, are reviewed. Major topics include construction of the pentacyclic ring system, stereoselective formation of 1,3-disubstituted beta-carboline and introduction of a double bond and cis glycol to the ring C of the pentacycle.