Kashin – Beck disease: From etiology to prevention or from prevention to etiology?
SUDRE, P. and MATHIEU, F.
International Orthopaedics 25. 175 – 179.
2001
บทคัดย่อ
A review with 30 references. The aetiology of KBD remains elusive. Four factors have been convincingly associated with the disease: selenium deficiency, iodine deficiency, grain contamination with mycotoxin – production fungi, and water pollution with organic material and fulvic acid. Although none of the competing theories prevails when they are compared using a predefined and standard set of causality criteria none should be discounted. This is an indication that a comprehensive and unifying theory is most likely to be multifactorial.