A quantitation risk assessment for fumonisins B1 and B2 in US corn.
HUMPHREYS, S.H., CARRINGTON, C and BOLGER, M.
Food Additives and Contaminants 18: 211 – 220.
2001
บทคัดย่อ
This analysis for exposure to fumonisin describes the magnitude of adverse effects, variability in the population and uncertainty of models as a range of possible outcomes. The most sensitive adverse response in rats, nephrotoxic lesions, was used for the sose – response analysis. Dietary intake of corn products were estimated by standard methods. Fumonisin levels in corn products were estimated from Food and Drug Administration surveillance data and distributions of fumonisin consumption were modelled for each eater in the survey population. Results of the dose – response and exposure analyses were assimilated in a two dimensional Monte – Carlo simulation. On the basis of this analysis, current dietary levels of fumonisin woluld not result in renal lesions even at upper levels of exposure.