บทคัดย่องานวิจัย

หมวดหมู่ : ฐานข้อมูลงานวิจัย

Terpendole M, a novel indolediterpenoid isolated from Lolium perenne infected with the endophytic fungus Neotyphodium lolii.

GATENBY, W.A., MUNDAY-FINCH, S.C., WILKINS, A.L. and MILES, C.O.

Journal of Agricultural and Food Chemistry 47 : 1092-1097.

1999

บทคัดย่อ

Terpendole M, a novel indolediterpenoid isolated from Lolium perenne infected with the endophytic fungus Neotyphodium lolii.

Terpendole M was isolated from perrennial ryegass ( Lolium perenne )  infected with the endophytic fungus  Neotyphodium lolii.  It was identified  as 14 alphahydroxyterpendole C by NMR and mass spectral techniques.  Paspaline and 13desoxypaxlline were also isolated from perennial ryegrass for the first time.  Terpendole M was lass tremorgenic then terpendole C in a standard mouse bioassay. These findings provide clues to the  biogenesis of the lolitrem neurotoxins as well as information on the structure-activity relationships within the indole-diterpenoids.