บทคัดย่องานวิจัย

Biosynthesis of 3-acetyldeoxynivalenol and sambucinol. Identification of the two oxygenation steps after trichodiene.

ZAMIR, L.O., NIKOLAKAKIS. A., HUANG, L.R., ST-PIERRE, P., SAURIOL, F., SPARACE, S. and MAMER, O.

Journal of Biological Chemistry 274 : 12269-12277.

1999

บทคัดย่อ

Biosynthesis of 3-acetyldeoxynivalenol and sambucinol. Identification of the two oxygenation steps after trichodiene.

The first two oxygenation steps posttrichodiene in the biosyntheses of 3-acetylDON and sambucinol were investigated.  It was shown that 2 alphahydroxytrichodiene is the first oxygenated step in the biosynthesis of both 3-acetylDON and sambucinol.  It was also demonstrated that the dioxygenated 12, 13-epoxy-9, 10-trichoene-2-alpha-ol is a biosynthetic precursor to trichothecenes.