Fusarie and 9,10-dehydrofusaric acids and their methyl esters from Fusarium nygamai.
Capasso, R., Evidente, A., Cutignano, A., Vurro, M.,Zonno, M.C. and Bottalica, A.
Phytochemistry 41 : 1035-1039.
1996
บทคัดย่อ
Fusaric and 9,10-dehydrofusaric acids and their corresponding methyl esters were isolated from the culture filtrates of Fusarium nygamai. The methyl esters were characterised by chemical and spectroscopic methods and reported here for the first time as naturally occurring products. When assayed on tomato leaves and seedlings, fusaric and 9,10-dehydrofusaric acids and their methyl esters showed wide chlorosis rapidly evolving into necrosis, as well as a strong inhibition of root elongation. When assayed on brine shrimps (Artemia salina), fusaric and 9,10-dehydrofusaric acids at 10-M were not toxic, however their methyl esters showed a toxicity level of 50%, expressed as mortality.