บทคัดย่องานวิจัย

Biosynthesis of norsolorinic acid and averufin-substrate specificity of norsolorinic acid synthase.

McKEOWN, D.S.J. McNICHOLAS, C., SIMPSON, T.J., and WILLETT, N.J.

Chemical Communications 1996 : 301-303.

1996

บทคัดย่อ

Biosynthesis of norsolorinic acid and averufin-substrate specificity of norsolorinic acid synthase.

The N-acetylcysteamine thioesters of pentanoic and 6-fluorohexanoic acids are metabolised by cultures of Aspergillus parasiticus to produce side chain modified analogues of norsolorinic acid in which the normal hexanoyl side chain is replaced by pentanoyl and 6-fluorohexanoyl moieties, respectively.