A new chlorinated phenylpyrrole antibiotic produced by the antifungal bacterium Pseudomonas cepacia.
Roitman, J. N.; Mahoney, N. E.; Janisiewicz, W. J.; Benson, M.;
Journal of Agricultural and Food Chemistry Year: 1990 Vol: 38 Issue: 2 Pages: 538-541 Ref: 13 ref.
1990
บทคัดย่อ
A group of chlorinated phenylpyrrole derivatives was isolated from a strain of P. cepacia collected from apple leaves during a screening programme to detect agents for biological control of fruit spoilage fungi. One of these substances, 2,3-dichloro-4-(2-amino-3-chlorophenyl)pyrrole, has not been previously reported. In vitro testing showed that all 4 phenylpyrroles had antifungal activity against several fruit pathogens. The new phenylpyrrole inhibited fungal growth on Golden Delicious apples inoculated with conidia of Penicillium expansum, Botrytis cinerea or Rhizopus sp. An unrelated but known compound, 2-(2-heptenyl)-3-methyl-4(1H)-quinolone, was also isolated.