บทคัดย่องานวิจัย

หมวดหมู่ : ฐานข้อมูลงานวิจัย

The antihistaminic chlorpheniramine inhibits in vitro growth of several fungi isolated from harvested fruits.

Tores, J. A., Gonzalez, M. D., Pozo, E., Urdiales, J. L., Medina, M. A. and Sanchez-Jimenez, F.

Phytoparasitica Year: 1999 Vol: 27 Issue: 3 Pages: 207-213 Ref: 17 ref.

1999

บทคัดย่อ

The antihistaminic chlorpheniramine inhibits in vitro growth of several fungi isolated from harvested fruits.

Chlorpheniramine (CPA) is an antihistaminic that changes the conformation of DNA and inhibits polyamine biosynthesis in mammalian cells. The effect of CPA on four genera of fungal species (Alternaria alternata, Botrytis cinerea, Cladosporium cladosporioides and three Penicillium spp.) was tested in vitro. Similar growth inhibitions of these genera were produced by 0.5 mM iprodione, CPA and histidinol, but CPA was the most effective. The CPA sensitivities of the two B. cinerea strains were different. Putrescine did not restore the fungal growth inhibited by CPA.