Umbelliferone, a phytoalexin associated with resistance of immature Marsh grapefruit to Penicillium digitatum.
Afek, U.; Orenstein, J.; Carmeli, S.; Rodov, V.; Joseph, M. B.;
Phytochemistry Year: 1999 Vol: 50 Issue: 7 Pages: 1129-1132 Ref: 17 ref.
1999
บทคัดย่อ
A low concentration (2 micro g FW) of 7-hydroxycoumarin (umbelliferone) was found in albedo of non-inoculated mature yellow Marsh grapefruit (Citrus paradisi). The concentration of umbelliferone in albedo of immature green grapefruit (2 months before full maturity) was 17 micro g/g FW. Four days following inoculation with Penicillium digitatum, the accumulation of umbelliferone in the albedo of mature and immature grapefruit was 28 and 250 micro g/g FW, respectively. By that period, the infected area in the yellow fruit was as large as 230 mm2, as compared with 8 mm2 in the green fruit. The EC50 of umbelliferone to P. digitatum growth in vitro was 95 micro g/ml. Additionally, umbelliferone inhibited growth of several other pathogenic fungi in vitro. It is suggested that umbelliferone plays a role in the defense mechanisms of immature grapefruit against P. digitatum.